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Distinct modes of cell competition shape mammalian tissue morphogenesis

Cell competition (CC)—the sensing and elimination of less fit “loser” cells by neighbouring “winner” cells—was first described in Drosophila. Although proposed as a selection mechanism to optimize tissue and organ development, its evolutionary generality remains unclear. Here, by employing live-imag...

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Detalles Bibliográficos
Autores principales: Ellis, Stephanie J., Gomez, Nicholas C., Levorse, John, Mertz, Aaron F., Ge, Yejing, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638572/
https://www.ncbi.nlm.nih.gov/pubmed/31092920
http://dx.doi.org/10.1038/s41586-019-1199-y