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EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection

During oropharyngeal candidiasis (OPC), Candida albicans proliferates and invades the superficial oral epithelium. Ephrin type-A receptor 2 (EphA2) functions as an oral epithelial cell β-glucan receptor that triggers the production of proinflammatory mediators in response to fungal infection. Becaus...

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Detalles Bibliográficos
Autores principales: Swidergall, Marc, Solis, Norma V., Wang, Zeping, Phan, Quynh T., Marshall, Michaela E., Lionakis, Michail S., Pearlman, Eric, Filler, Scott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638578/
https://www.ncbi.nlm.nih.gov/pubmed/31291578
http://dx.doi.org/10.1016/j.celrep.2019.06.020