Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli

Polyketides are a class of specialised metabolites synthesised by both eukaryotes and prokaryotes. These chemically and structurally diverse molecules are heavily used in the clinic and include frontline antimicrobial and anticancer drugs such as erythromycin and doxorubicin. To replenish the clinic...

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Detalles Bibliográficos
Autores principales: Cummings, Matthew, Peters, Anna D., Whitehead, George F. S., Menon, Binuraj R. K., Micklefield, Jason, Webb, Simon J., Takano, Eriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638757/
https://www.ncbi.nlm.nih.gov/pubmed/31318855
http://dx.doi.org/10.1371/journal.pbio.3000347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638757/
https://www.ncbi.nlm.nih.gov/pubmed/31318855
http://dx.doi.org/10.1371/journal.pbio.3000347

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