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Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli
Polyketides are a class of specialised metabolites synthesised by both eukaryotes and prokaryotes. These chemically and structurally diverse molecules are heavily used in the clinic and include frontline antimicrobial and anticancer drugs such as erythromycin and doxorubicin. To replenish the clinic...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638757/ https://www.ncbi.nlm.nih.gov/pubmed/31318855 http://dx.doi.org/10.1371/journal.pbio.3000347 |