Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies

Gene-environment (GxE) interaction is one potential explanation for the missing heritability problem. A popular approach to genome-wide environment interaction studies (GWEIS) is based on regression models involving interactions between genetic variants and environment variables. Unfortunately, GWEI...

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Detalles Bibliográficos
Autores principales: Ueki, Masao, Fujii, Masahiro, Tamiya, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638962/
https://www.ncbi.nlm.nih.gov/pubmed/31318927
http://dx.doi.org/10.1371/journal.pone.0219825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638962/
https://www.ncbi.nlm.nih.gov/pubmed/31318927
http://dx.doi.org/10.1371/journal.pone.0219825

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