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Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies
Gene-environment (GxE) interaction is one potential explanation for the missing heritability problem. A popular approach to genome-wide environment interaction studies (GWEIS) is based on regression models involving interactions between genetic variants and environment variables. Unfortunately, GWEI...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638962/ https://www.ncbi.nlm.nih.gov/pubmed/31318927 http://dx.doi.org/10.1371/journal.pone.0219825 |