Androgen Deprivation Leads to Increased Carbohydrate Metabolism and Hexokinase 2 Mediated Survival in Pten/Tp53 Deficient Prostate Cancer

Prostate cancer is characterized by a dependence upon androgen receptor (AR) signaling, and androgen deprivation therapy (ADT) is the accepted treatment for progressive prostate cancer. Although ADT is usually initially effective, acquired resistance, termed castrate resistant prostate cancer (CRPC)...

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Detalles Bibliográficos
Autores principales: Martin, Philip L., Yin, Juan-Juan, Seng, Victoria, Casey, Orla, Corey, Eva, Morrissey, Colm, Simpson, R. Mark, Kelly, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639059/
https://www.ncbi.nlm.nih.gov/pubmed/27375016
http://dx.doi.org/10.1038/onc.2016.223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639059/
https://www.ncbi.nlm.nih.gov/pubmed/27375016
http://dx.doi.org/10.1038/onc.2016.223

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