HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon

The bacterial Sec translocon is a multi-protein complex responsible for translocating diverse proteins across the plasma membrane. For post-translational protein translocation, the Sec-channel – SecYEG – associates with the motor protein SecA to mediate the ATP-dependent transport of pre-proteins ac...

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Detalles Bibliográficos
Autores principales: Ahdash, Zainab, Pyle, Euan, Allen, William John, Corey, Robin A, Collinson, Ian, Politis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639072/
https://www.ncbi.nlm.nih.gov/pubmed/31290743
http://dx.doi.org/10.7554/eLife.47402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639072/
https://www.ncbi.nlm.nih.gov/pubmed/31290743
http://dx.doi.org/10.7554/eLife.47402

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