Cargando…

KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone

We previously showed that KLF4, a gene highly expressed in murine prostate stem cells, blocks the progression of indolent intraepithelial prostatic lesions into aggressive and rapidly growing tumors. Here we show that the anti-tumorigenic effect of KLF4 extends to PC3 human prostate cancer cells gro...

Descripción completa

Detalles Bibliográficos
Autores principales: Tassone, Evelyne, Bradaschia-Correa, Vivian, Xiong, Xiaozhong, Sastre-Perona, Ana, Josephson, Anne Marie, Khodadadi-Jamayran, Alireza, Melamed, Jonathan, Bu, Lei, Kahler, David J, Ossowski, Liliana, Leucht, Philipp, Schober, Markus, Wilson, Elaine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639130/
https://www.ncbi.nlm.nih.gov/pubmed/31239516
http://dx.doi.org/10.1038/s41388-019-0841-3