SOD1 is essential for oncogene-driven mammary tumor formation but dispensable for normal development and proliferation.

We previously reported that the dismutase SOD1 is overexpressed in breast cancer. However, whether SOD1 plays an active role in tumor formation in vivo has never been demonstrated. Further, as luminal cells of normal breast epithelial cells are enriched in SOD1, whether SOD1 is essential for normal...

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Detalles Bibliográficos
Autores principales: Gomez, Maria, Shah, Nagma, Kenny, Timothy C., Jenkins, Edmund C., Germain, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639133/
https://www.ncbi.nlm.nih.gov/pubmed/31222103
http://dx.doi.org/10.1038/s41388-019-0839-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639133/
https://www.ncbi.nlm.nih.gov/pubmed/31222103
http://dx.doi.org/10.1038/s41388-019-0839-x

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