Promyelocytic leukemia protein deficiency leads to spontaneous formation of liver tumors in hepatitis C virus transgenic mice

Persistent infection with hepatitis C virus (HCV) is a known risk factor for the development of hepatocellular carcinoma (HCC). The lack of the tumor suppressor promyelocytic leukemia protein (PML) in combination with HCV fosters hepatocarcinogenesis via induction of HCC using diethylnitrosamine (DE...

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Detalles Bibliográficos
Autores principales: Straub, Katja, Husen, Peri, Baba, Hideo A., Trippler, Martin, Wedemeyer, Heiner, Herzer, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639172/
https://www.ncbi.nlm.nih.gov/pubmed/31144474
http://dx.doi.org/10.1002/cam4.2162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639172/
https://www.ncbi.nlm.nih.gov/pubmed/31144474
http://dx.doi.org/10.1002/cam4.2162

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