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Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer

PURPOSE: Recurrence and chemoresistance (CR) are the leading causes of death in patients with high-grade serous carcinoma (HGSC) of the ovary. The aim of this study was to identify genetic changes associated with CR mechanisms using a patient-derived xenograft (PDX) mouse model and genetic sequencin...

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Detalles Bibliográficos
Autores principales: Li, Lan Ying, Kim, Hee Jung, Park, Sun Ae, Lee, So Hyun, Kim, Lee Kyung, Lee, Jung Yun, Kim, Sunghoon, Kim, Young Tae, Kim, Sang Wun, Nam, Eun Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639203/
https://www.ncbi.nlm.nih.gov/pubmed/30428638
http://dx.doi.org/10.4143/crt.2018.405