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Prevalence of PALB2 Germline Mutations in Early-onset and Familial Breast/Ovarian Cancer Patients from Pakistan

PURPOSE: Partner and localizer of BRCA2 (PALB2) is a breast cancer susceptibility gene that plays an important role in DNA repair. This is the first study assessing the prevalence of PALB2 mutations in early-onset and familial breast/ovarian cancer patients from Pakistan. MATERIALS AND METHODS: PALB...

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Detalles Bibliográficos
Autores principales: Rashid, Muhammad Usman, Khan, Faiz Ali, Muhammad, Noor, Loya, Asif, Hamann, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639217/
https://www.ncbi.nlm.nih.gov/pubmed/30309218
http://dx.doi.org/10.4143/crt.2018.356