Cargando…

Prevalence of PALB2 Germline Mutations in Early-onset and Familial Breast/Ovarian Cancer Patients from Pakistan

PURPOSE: Partner and localizer of BRCA2 (PALB2) is a breast cancer susceptibility gene that plays an important role in DNA repair. This is the first study assessing the prevalence of PALB2 mutations in early-onset and familial breast/ovarian cancer patients from Pakistan. MATERIALS AND METHODS: PALB...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rashid, Muhammad Usman, Khan, Faiz Ali, Muhammad, Noor, Loya, Asif, Hamann, Ute
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Cancer Association 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639217/ https://www.ncbi.nlm.nih.gov/pubmed/30309218 http://dx.doi.org/10.4143/crt.2018.356

Ejemplares similares

Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2020)

Correction to: Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2021)

Spectrum and prevalence of BRCA1/2 germline mutations in Pakistani breast cancer patients: results from a large comprehensive study
por: Rashid, Muhammad Usman, et al.
Publicado: (2019)

Constitutional CHEK2 mutations are infrequent in early-onset and familial breast/ovarian cancer patients from Pakistan
por: Rashid, Muhammad U, et al.
Publicado: (2013)

High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2016)

A novel deleterious c.2656G>T MSH2 germline mutation in a Pakistani family with a phenotypic overlap of hereditary breast and ovarian cancer and Lynch syndrome
por: Rashid, Muhammad U., et al.
Publicado: (2016)

Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study
por: Rashid, Muhammad Usman, et al.
Publicado: (2015)

Germline PALB2 Mutation in High-Risk Chinese Breast and/or Ovarian Cancer Patients
por: Kwong, Ava, et al.
Publicado: (2021)

Germline PALB2 Mutations in Cancers and Its Distinction From Somatic PALB2 Mutations in Breast Cancers
por: Hu, Zhe-Yu, et al.
Publicado: (2020)

Prevalence and spectrum of MLH1, MSH2, and MSH6 pathogenic germline variants in Pakistani colorectal cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2019)

Tumour morphology predicts PALB2 germline mutation status
por: Teo, Z L, et al.
Publicado: (2013)

PALB2 germline mutations in a large cohort of Middle Eastern breast-ovarian cancer patients
por: Siraj, Abdul K., et al.
Publicado: (2023)

Prevalence of BRCA1 and BRCA2 germline variants in an unselected pancreatic cancer patient cohort in Pakistan
por: Muhammad, Noor, et al.
Publicado: (2023)

A novel germline PALB2 deletion in Polish breast and ovarian cancer patients
por: Dansonka-Mieszkowska, Agnieszka, et al.
Publicado: (2010)

Evolutionary Origin of Human PALB2 Germline Pathogenic Variants
por: Chian, Jia Sheng, et al.
Publicado: (2023)

Next Generation Sequencing-Based Germline Panel Testing for Breast and Ovarian Cancers in Pakistan
por: Tariq, Hassan, et al.
Publicado: (2021)

Association between Cyclooxygenase-2 and Indoleamine 2,3-Dioxygenase Expression in Breast Cancer Patients from Pakistan
por: Asghar, Kashif, et al.
Publicado: (2019)

Case Report: Co-Existence of BRCA2 and PALB2 Germline Mutations in Familial Prostate Cancer With Solitary Lung Metastasis
por: Tang, Tang, et al.
Publicado: (2020)

Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families
por: Teo, Zhi L, et al.
Publicado: (2013)

Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls
por: Thompson, Ella R., et al.
Publicado: (2015)

Prevalence of BRCA1 and BRCA2 Germline Mutations in Patients of African Descent with Early-Onset and Familial Colombian Breast Cancer
por: Vargas, Elizabeth, et al.
Publicado: (2022)

Report of a germline double heterozygote in MSH2 and PALB2
por: Agiannitopoulos, Konstantinos, et al.
Publicado: (2020)

Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance
por: Horak, Peter, et al.
Publicado: (2019)

Clinical Characteristics of COVID-19-Infected Cancer Patients in Pakistan: Differences Between Survivors and Non-Survivors
por: Asghar, Kashif, et al.
Publicado: (2021)

Familial wild-type gastrointestinal stromal tumour in association with germline truncating variants in both SDHA and PALB2
por: Whitworth, James, et al.
Publicado: (2021)

Spectrum of PALB2 germline mutations and characteristics of PALB2‐related breast cancer: Screening of 16,501 unselected patients with breast cancer and 5890 controls by next‐generation sequencing
por: Zhou, Jiaojiao, et al.
Publicado: (2020)

Germline Mutations of Inhibins in Early-Onset Ovarian Epithelial Tumors
por: Tournier, Isabelle, et al.
Publicado: (2014)

Intronic TP53 Germline Sequence Variants Modify the Risk in German Breast/Ovarian Cancer Families
por: Liu, Xuan, et al.
Publicado: (2004)

Germline PALB2, ATM variants in a patient with breast and ovarian cancer at risk for familial cancer syndrome: Is there a role for risk-reducing salpingo-oophorectomy?
por: Carbajal-Mamani, Semiramis L., et al.
Publicado: (2020)

PALB2 Variants Extend the Mutational Profile of Hungarian Patients with Breast and Ovarian Cancer
por: Butz, Henriett, et al.
Publicado: (2023)

Impact of Protracted Displacement on Delay in the Diagnosis Associated with Treatment Outcomes: A Cross-Sectional Study in Internally Displaced Tuberculosis Patients of Pakistan
por: Khan, Farman Ullah, et al.
Publicado: (2021)

Case Report: Effectiveness of Targeted Treatment in a Patient With Pancreatic Cancer Harboring PALB2 Germline Mutation and KRAS Somatic Mutation
por: Wu, Wei, et al.
Publicado: (2022)

Olaparib for metastatic breast cancer in a patient with a germline PALB2 variant
por: Kuemmel, Sherko, et al.
Publicado: (2020)

Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation
por: Wattenberg, Max M., et al.
Publicado: (2019)

PALB2 mutations in BRCA1/2-mutation negative breast and ovarian cancer patients from Poland
por: Kluska, Anna, et al.
Publicado: (2017)

A germline PALB2 pathogenic variant identified in a pediatric high-grade glioma
por: Zhong, Yiming, et al.
Publicado: (2020)

Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada
por: Hartley, Taila, et al.
Publicado: (2014)

Prevalence and associated risk factors among patients with overactive bladder syndrome in Pakistan
por: Rashid, Sajid, et al.
Publicado: (2021)

No evidence for PALB2 methylation in high-grade serous ovarian cancer
por: Mikeska, Thomas, et al.
Publicado: (2013)

Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study
por: Fewings, Eleanor, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_e03nk2o9vv258aiv5ocl9aedrf