Therapeutic Targeting of the DNA Damage Response Using an ATR Inhibitor in Biliary Tract Cancer

PURPOSE: The DNA damage response (DDR) is a multi-complex network of signaling pathways involved in DNA damage repair, cell cycle checkpoints, and apoptosis. In the case of biliary tract cancer (BTC), the strategy of DDR targeting has not been evaluated, even though many patients have DNA repair pat...

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Detalles Bibliográficos
Autores principales: Nam, Ah-Rong, Jin, Mei Hua, Park, Ji Eun, Bang, Ju-Hee, Oh, Do-Youn, Bang, Yung-Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639230/
https://www.ncbi.nlm.nih.gov/pubmed/30514066
http://dx.doi.org/10.4143/crt.2018.526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639230/
https://www.ncbi.nlm.nih.gov/pubmed/30514066
http://dx.doi.org/10.4143/crt.2018.526

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