Selective Kinase Inhibition Shows That Bur1 (Cdk9) Phosphorylates the Rpb1 Linker In Vivo

Cyclin-dependent kinases play multiple roles in RNA polymerase II transcription. Cdk7/Kin28, Cdk9/Bur1, and Cdk12/Ctk1 phosphorylate the polymerase and other factors to drive the dynamic exchange of initiation and elongation complex components over the transcription cycle. We engineered strains of t...

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Detalles Bibliográficos
Autores principales: Chun, Yujin, Joo, Yoo Jin, Suh, Hyunsuk, Batot, Gaëlle, Hill, Christopher P., Formosa, Tim, Buratowski, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639251/
https://www.ncbi.nlm.nih.gov/pubmed/31085683
http://dx.doi.org/10.1128/MCB.00602-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639251/
https://www.ncbi.nlm.nih.gov/pubmed/31085683
http://dx.doi.org/10.1128/MCB.00602-18

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