Identification of Ebola Virus Inhibitors Targeting GP2 Using Principles of Molecular Mimicry

A key step in the Ebola virus (EBOV) replication cycle involves conformational changes in viral glycoprotein 2 (GP2) which facilitate host-viral membrane fusion and subsequent release of the viral genome. Ebola GP2 plays a critical role in virus entry and has similarities in mechanism and structure...

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Detalles Bibliográficos
Autores principales: Singleton, Courtney D., Humby, Monica S., Yi, Hyun Ah, Rizzo, Robert C., Jacobs, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639268/
https://www.ncbi.nlm.nih.gov/pubmed/31092576
http://dx.doi.org/10.1128/JVI.00676-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639268/
https://www.ncbi.nlm.nih.gov/pubmed/31092576
http://dx.doi.org/10.1128/JVI.00676-19

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