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GII.13/21 Noroviruses Recognize Glycans with a Terminal β-Galactose via an Unconventional Glycan Binding Site

Human noroviruses (huNoVs) recognize histo-blood group antigens (HBGAs) as host susceptibility factors. GII.13 and GII.21 huNoVs form a unique genetic lineage that emerged from mainstream GII NoVs via development of a new, nonconventional glycan binding site (GBS) that binds Le(a) antigen. This prev...

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Detalles Bibliográficos
Autores principales: Cong, Xin, Sun, Xiao-man, Qi, Jian-xun, Li, Han-bo, Chai, Wen-gang, Zhang, Qing, Wang, Hong, Kong, Xiang-yu, Song, Jiao, Pang, Li-li, Jin, Miao, Li, Dan-di, Tan, Ming, Duan, Zhao-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639292/
https://www.ncbi.nlm.nih.gov/pubmed/31118252
http://dx.doi.org/10.1128/JVI.00723-19