Anti-apoptotic activity of ET(B) receptor agonist, IRL-1620, protects neural cells in rats with cerebral ischemia

Endothelin-B receptor agonist, IRL-1620, provides significant neuroprotection following cerebral ischemia in rats. Whether this neuroprotection is due to inhibition of apoptosis is unknown. IRL-1620-treated rats following permanent middle cerebral artery occlusion (MCAO) showed significant improveme...

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Detalles Bibliográficos
Autores principales: Briyal, Seema, Ranjan, Amaresh K., Hornick, Mary G., Puppala, Anupama K., Luu, Thanh, Gulati, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639304/
https://www.ncbi.nlm.nih.gov/pubmed/31320660
http://dx.doi.org/10.1038/s41598-019-46203-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639304/
https://www.ncbi.nlm.nih.gov/pubmed/31320660
http://dx.doi.org/10.1038/s41598-019-46203-x

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