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Anti-apoptotic activity of ET(B) receptor agonist, IRL-1620, protects neural cells in rats with cerebral ischemia
Endothelin-B receptor agonist, IRL-1620, provides significant neuroprotection following cerebral ischemia in rats. Whether this neuroprotection is due to inhibition of apoptosis is unknown. IRL-1620-treated rats following permanent middle cerebral artery occlusion (MCAO) showed significant improveme...
Autores principales: | Briyal, Seema, Ranjan, Amaresh K., Hornick, Mary G., Puppala, Anupama K., Luu, Thanh, Gulati, Anil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639304/ https://www.ncbi.nlm.nih.gov/pubmed/31320660 http://dx.doi.org/10.1038/s41598-019-46203-x |
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