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Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing

Androgens are known to be an essential regulator of male health. Androgen receptor (AR) is widely expressed throughout the adrenal cortex, yet the wider role for androgen signalling in the adrenal remains underexplored. To investigate AR-dependent and AR-independent androgen signalling in the adrena...

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Detalles Bibliográficos
Autores principales: Gannon, Anne-Louise, O’Hara, Laura, Mason, J. Ian, Jørgensen, Anne, Frederiksen, Hanne, Milne, Laura, Smith, Sarah, Mitchell, Rod T., Smith, Lee B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639311/
https://www.ncbi.nlm.nih.gov/pubmed/31320667
http://dx.doi.org/10.1038/s41598-019-46049-3