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Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
Androgens are known to be an essential regulator of male health. Androgen receptor (AR) is widely expressed throughout the adrenal cortex, yet the wider role for androgen signalling in the adrenal remains underexplored. To investigate AR-dependent and AR-independent androgen signalling in the adrena...
Autores principales: | Gannon, Anne-Louise, O’Hara, Laura, Mason, J. Ian, Jørgensen, Anne, Frederiksen, Hanne, Milne, Laura, Smith, Sarah, Mitchell, Rod T., Smith, Lee B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639311/ https://www.ncbi.nlm.nih.gov/pubmed/31320667 http://dx.doi.org/10.1038/s41598-019-46049-3 |
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