PLPP/CIN-mediated NEDD4-2 S448 dephosphorylation regulates neuronal excitability via GluA1 ubiquitination

Neuronal precursor cell expressed developmentally downregulated 4-2 (NEDD4-2) is an E3 ubiquitin ligase to regulate ion transport by controlling cellular trafficking/endocytosis and lysosomal degradation of ion channels and transporters. Thus, NEDD4-2 is relevant to neuronal excitability and epilept...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Lee, Duk-Shin, Kim, Min Ju, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639327/
https://www.ncbi.nlm.nih.gov/pubmed/31320629
http://dx.doi.org/10.1038/s41419-019-1781-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639327/
https://www.ncbi.nlm.nih.gov/pubmed/31320629
http://dx.doi.org/10.1038/s41419-019-1781-0

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