Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia

Extremely reduced oxygen (O(2)) levels are detrimental to myogenic differentiation and multinucleated myotube formation, and chronic exposure to high-altitude hypoxia has been reported to be an important factor in skeletal muscle atrophy. However, how chronic hypoxia causes muscle dysfunction remain...

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Detalles Bibliográficos
Autores principales: Zhang, Zhang, Zhang, Liqiang, Zhou, You, Li, Liya, Zhao, Jiangdong, Qin, Wen, Jin, Zuolin, Liu, Wenjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639330/
https://www.ncbi.nlm.nih.gov/pubmed/31320610
http://dx.doi.org/10.1038/s41419-019-1763-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639330/
https://www.ncbi.nlm.nih.gov/pubmed/31320610
http://dx.doi.org/10.1038/s41419-019-1763-2

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