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The natural compound neobractatin inhibits tumor metastasis by upregulating the RNA-binding-protein MBNL2

Tumor metastasis is the predominant cause of lethality in cancer. We found that Neobractatin (NBT), a natural compound isolated from Garcinia bracteata, could efficiently inhibit breast and lung cancer cells metastasis. However, the mechanisms of NBT inhibiting cancer metastasis remain unclear. Base...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Zheng, Zhaoqing, Wu, Man, Zhang, Li, Wang, Jing, Fu, Wenwei, Xu, Naihan, Zhao, Zhili, Lao, Yuanzhi, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639345/
https://www.ncbi.nlm.nih.gov/pubmed/31320607
http://dx.doi.org/10.1038/s41419-019-1789-5