PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway

Unfolded protein response (UPR) is an adaptive mechanism that aims at restoring ER homeostasis under severe environmental stress. Malignant cells are resistant to environmental stress, which is largely due to an activated UPR. However, the molecular mechanisms by which different UPR branches are sel...

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Detalles Bibliográficos
Autores principales: Shin, Gu-Choul, Moon, Sung Ung, Kang, Hong Seok, Choi, Hyo-Sun, Han, Hee Dong, Kim, Kyun-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639383/
https://www.ncbi.nlm.nih.gov/pubmed/31320625
http://dx.doi.org/10.1038/s41467-019-11019-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639383/
https://www.ncbi.nlm.nih.gov/pubmed/31320625
http://dx.doi.org/10.1038/s41467-019-11019-w

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