Cargando…
PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway
Unfolded protein response (UPR) is an adaptive mechanism that aims at restoring ER homeostasis under severe environmental stress. Malignant cells are resistant to environmental stress, which is largely due to an activated UPR. However, the molecular mechanisms by which different UPR branches are sel...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639383/ https://www.ncbi.nlm.nih.gov/pubmed/31320625 http://dx.doi.org/10.1038/s41467-019-11019-w |