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Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

mRNA transport restricts translation to specific subcellular locations, which is the basis for many cellular functions. However, the precise process of mRNA sorting to synapses in neurons remains elusive. Here we use Rgs4 mRNA to investigate 3′-UTR-dependent transport by MS2 live-cell imaging. The m...

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Detalles Bibliográficos
Autores principales: Bauer, Karl E., Segura, Inmaculada, Gaspar, Imre, Scheuss, Volker, Illig, Christin, Ammer, Georg, Hutten, Saskia, Basyuk, Eugénia, Fernández-Moya, Sandra M., Ehses, Janina, Bertrand, Edouard, Kiebler, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639396/
https://www.ncbi.nlm.nih.gov/pubmed/31320644
http://dx.doi.org/10.1038/s41467-019-11123-x