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Plasma and tissue angiotensin‐converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease

BACKGROUND: Angiotensin‐converting enzyme 2 (ACE2) is a homologue of angiotensin‐converting enzyme (ACE) and produces angiotensin peptides (APs), such as angiotensin 1‐9 and 1‐7 that are vasodilatory and natriuretic, and act to counterbalance angiotensin II. HYPOTHESIS: Evidence of ACE2 can be found...

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Detalles Bibliográficos
Autores principales: Larouche‐Lebel, Éva, Loughran, Kerry A., Oyama, Mark A., Solter, Phil F., Laughlin, Danielle S., Sánchez, Melissa D., Assenmacher, Charles‐Antoine, Fox, Philip R., Fries, Ryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639469/
https://www.ncbi.nlm.nih.gov/pubmed/31254308
http://dx.doi.org/10.1111/jvim.15548