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Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis

BACKGROUND: DNA methylation, acknowledged as a key modification in the field of epigenetics, regulates gene expression at the transcriptional level. Aberrant methylation in DNA regulatory regions could upregulate oncogenes and downregulate tumor suppressor genes without changing the sequences. Howev...

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Detalles Bibliográficos
Autores principales: Liang, Yu, Zhang, Cheng, Dai, Dong-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639549/
https://www.ncbi.nlm.nih.gov/pubmed/31341364
http://dx.doi.org/10.3748/wjg.v25.i26.3392