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Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis
BACKGROUND: DNA methylation, acknowledged as a key modification in the field of epigenetics, regulates gene expression at the transcriptional level. Aberrant methylation in DNA regulatory regions could upregulate oncogenes and downregulate tumor suppressor genes without changing the sequences. Howev...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639549/ https://www.ncbi.nlm.nih.gov/pubmed/31341364 http://dx.doi.org/10.3748/wjg.v25.i26.3392 |