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Polygenetic risk for coronary artery disease increases hospitalization burden and mortality

BACKGROUND: Coronary artery disease (CAD) is a leading cause of death worldwide and increasing cost for society. Genome wide association studies (GWAS) have identified common variants associated with CAD. Combining single nucleotide polymorphisms (SNPs) into a genetic risk score (GRS) can estimate a...

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Detalles Bibliográficos
Autores principales: Sjögren, Marketa, Almgren, Peter, Melander, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639589/
https://www.ncbi.nlm.nih.gov/pubmed/31360760
http://dx.doi.org/10.1016/j.ijcha.2019.100391