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Divergent Effects of a Transient Corticosteroid Therapy on Virus-Specific Quiescent and Effector CD8(+) T Cells
We investigated the influence of a transient treatment of corticosteroid on CD8(+) T cells during herpesvirus infection. Dexamethasone, a synthetic corticosteroid, induced apoptosis of naïve and memory CD8(+) T cells but virus-specific effector cells were spared. CD8(+) T cell susceptibility was dir...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639716/ https://www.ncbi.nlm.nih.gov/pubmed/31354707 http://dx.doi.org/10.3389/fimmu.2019.01521 |