Cargando…

Divergent Effects of a Transient Corticosteroid Therapy on Virus-Specific Quiescent and Effector CD8(+) T Cells

We investigated the influence of a transient treatment of corticosteroid on CD8(+) T cells during herpesvirus infection. Dexamethasone, a synthetic corticosteroid, induced apoptosis of naïve and memory CD8(+) T cells but virus-specific effector cells were spared. CD8(+) T cell susceptibility was dir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Dhaneshwar, Sehrawat, Sharvan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639716/ https://www.ncbi.nlm.nih.gov/pubmed/31354707 http://dx.doi.org/10.3389/fimmu.2019.01521

Ejemplares similares

Galectin-3 Regulates γ-Herpesvirus Specific CD8 T Cell Immunity
por: Kaur, Manpreet, et al.
Publicado: (2018)

Herpesviruses: Harmonious Pathogens but Relevant Cofactors in Other Diseases?
por: Sehrawat, Sharvan, et al.
Publicado: (2018)

Interplay of Regulatory T Cell and Th17 Cells during Infectious Diseases in Humans and Animals
por: Sehrawat, Sharvan, et al.
Publicado: (2017)

Galectin-9/TIM-3 Interaction Regulates Virus-Specific Primary and Memory CD8(+) T Cell Response
por: Sehrawat, Sharvan, et al.
Publicado: (2010)

Transient Depletion of CD169(+) Cells Contributes to Impaired Early Protection and Effector CD8(+) T Cell Recruitment against Mucosal Respiratory Syncytial Virus Infection
por: Oh, Dong Sun, et al.
Publicado: (2017)

Tumor Infiltrating Effector Memory Antigen-Specific CD8(+) T Cells Predict Response to Immune Checkpoint Therapy
por: Principe, Nicola, et al.
Publicado: (2020)

Perspective: Reducing SARS-CoV2 Infectivity and Its Associated Immunopathology
por: Dubey, Abhishek, et al.
Publicado: (2020)

Controlling viral inflammatory lesions by rebalancing immune response patterns
por: Mulik, Sachin, et al.
Publicado: (2023)

Impact of Inflammatory Cytokines on Effector and Memory CD8+ T Cells
por: Kim, Marie T., et al.
Publicado: (2014)

Optical Control of CD8(+) T Cell Metabolism and Effector Functions
por: Amitrano, Andrea M., et al.
Publicado: (2021)

Subretinal Injection of HY Peptides Induces Systemic Antigen-Specific Inhibition of Effector CD4(+) and CD8(+) T-Cell Responses
por: Vendomèle, Julie, et al.
Publicado: (2018)

Effector CD8 T Cell-Dependent Zika Virus Control in the CNS: A Matter of Time and Numbers
por: Nazerai, Loulieta, et al.
Publicado: (2020)

Transcriptional and Epigenetic Regulation of Effector and Memory CD8 T Cell Differentiation
por: Chen, Yao, et al.
Publicado: (2018)

Metabolic alterations impair differentiation and effector functions of CD8+ T cells
por: Bensussen, Antonio, et al.
Publicado: (2022)

The Significance of Tumor Necrosis Factor Receptor Type II in CD8(+) Regulatory T Cells and CD8(+) Effector T Cells
por: Ye, Lin-Lin, et al.
Publicado: (2018)

Protocol for investigating the biogenesis of SARS-CoV-2 S pseudoviruses in HEK293T cells transduced to express the virus-specific intrabodies
por: Dahiya, Surbhi, et al.
Publicado: (2022)

Kinetics of CD4(+) T Helper and CD8(+) Effector T Cell Responses in Acute Dengue Patients
por: Manh, Dao Huy, et al.
Publicado: (2020)

Notch controls effector CD8(+) T cell differentiation
por: Duval, Frédéric, et al.
Publicado: (2015)

Immunity and immunopathology to viruses: what decides the outcome?
por: Rouse, Barry T., et al.
Publicado: (2010)

Cognate Antigen Stimulation Generates Potent CD8(+) Inflammatory Effector T Cells
por: Sung, Hsueh-Cheng, et al.
Publicado: (2013)

WASp Is Essential for Effector-to-Memory conversion and for Maintenance of CD8(+)T Cell Memory
por: Liu, Qiao, et al.
Publicado: (2019)

TNF Blockade Maintains an IL-10(+) Phenotype in Human Effector CD4(+) and CD8(+) T Cells
por: Roberts, Ceri A., et al.
Publicado: (2017)

Naringenin Modifies the Development of Lineage-Specific Effector CD4(+) T Cells
por: Wang, Junpeng, et al.
Publicado: (2018)

Effector and Central Memory Poly-Functional CD4(+) and CD8(+) T Cells are Boosted upon ZOSTAVAX(®) Vaccination
por: Sei, Janet J., et al.
Publicado: (2015)

Reduced CD5 on CD8(+) T Cells in Tumors but Not Lymphoid Organs Is Associated With Increased Activation and Effector Function
por: Alotaibi, Faizah, et al.
Publicado: (2021)

The smallest unit: effector and memory CD8(+) T cell differentiation on the single cell level
por: Buchholz, Veit R., et al.
Publicado: (2013)

Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells
por: Wells, Alexandria C, et al.
Publicado: (2017)

Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus
por: Devarajan, Priyadharshini, et al.
Publicado: (2018)

Chronic CD27-CD70 costimulation promotes type 1-specific polarization of effector Tregs
por: Bowakim-Anta, Natalia, et al.
Publicado: (2023)

An extrafollicular pathway for the generation of effector CD8(+) T cells driven by the proinflammatory cytokine, IL-12
por: Shah, Suhagi, et al.
Publicado: (2015)

G-Protein Coupled Receptor 18 Contributes to Establishment of the CD8 Effector T Cell Compartment
por: Sumida, Hayakazu, et al.
Publicado: (2018)

Regulation of Effector and Memory CD8 T Cell Differentiation by IL-2—A Balancing Act
por: Kalia, Vandana, et al.
Publicado: (2018)

Cheating the Hunger Games; Mechanisms Controlling Clonal Diversity of CD8 Effector and Memory Populations
por: Kavazović, Inga, et al.
Publicado: (2018)

Differentially Expressed Potassium Channels Are Associated with Function of Human Effector Memory CD8(+) T Cells
por: Sim, Ji Hyun, et al.
Publicado: (2017)

Treg and Oligoclonal Expansion of Terminal Effector CD8(+) T Cell as Key Players in Multiple Myeloma
por: Joshua, Douglas E., et al.
Publicado: (2021)

Macrophages—the immune effector guardians of the lung: impact of corticosteroids on their functional responses
por: van Eeden, Stephan F., et al.
Publicado: (2020)

Functional Change of Effector Tumor-Infiltrating CCR5(+)CD38(+)HLA-DR(+)CD8(+) T Cells in Glioma Microenvironment
por: Chen, Pin-Yuan, et al.
Publicado: (2019)

CD8 Effector T Cells Function Synergistically With Broadly Neutralizing Antibodies to Enhance Suppression of HIV Infection
por: Veenhuis, Rebecca T., et al.
Publicado: (2021)

Differentiation of Memory CD8 T Cells Unravel Gene Expression Pattern Common to Effector and Memory Precursors
por: Neitzke-Montinelli, Vanessa, et al.
Publicado: (2022)

CMV-Specific CD8 T Cell Differentiation and Localization: Implications for Adoptive Therapies
por: Smith, Corinne J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vdtd9i68jsqs8dhbjt0qb3kd0c