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Targeted insertion of large DNA sequences by homology‐directed repair or non‐homologous end joining in engineered tobacco BY‐2 cells using designed zinc finger nucleases

Targeted integration of recombinant DNA fragments into plant genomes by DNA double‐strand break (DSB) repair mechanisms has become a powerful tool for precision engineering of crops. However, many targeting platforms require the screening of many transgenic events to identify a low number of targete...

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Detalles Bibliográficos
Autores principales: Schiermeyer, Andreas, Schneider, Katja, Kirchhoff, Janina, Schmelter, Thomas, Koch, Natalie, Jiang, Ke, Herwartz, Denise, Blue, Ryan, Marri, Pradeep, Samuel, Pon, Corbin, David R., Webb, Steven R., Gonzalez, Delkin O., Folkerts, Otto, Fischer, Rainer, Schinkel, Helga, Ainley, W. Michael, Schillberg, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639735/
https://www.ncbi.nlm.nih.gov/pubmed/31360827
http://dx.doi.org/10.1002/pld3.153