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FunFam protein families improve residue level molecular function prediction

BACKGROUND: The CATH database provides a hierarchical classification of protein domain structures including a sub-classification of superfamilies into functional families (FunFams). We analyzed the similarity of binding site annotations in these FunFams and incorporated FunFams into the prediction o...

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Detalles Bibliográficos
Autores principales: Scheibenreif, Linus, Littmann, Maria, Orengo, Christine, Rost, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639920/
https://www.ncbi.nlm.nih.gov/pubmed/31319797
http://dx.doi.org/10.1186/s12859-019-2988-x