Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

BACKGROUND: Molecular markers for prostate cancer (PCa) are required to improve the early definition of patient outcomes. Atypically large extracellular vesicles (EVs), referred as “Large Oncosomes” (LO), have been identified in highly migratory and invasive PCa cells. We recently developed and char...

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Detalles Bibliográficos
Autores principales: Ciardiello, Chiara, Leone, Alessandra, Lanuti, Paola, Roca, Maria S., Moccia, Tania, Minciacchi, Valentina R., Minopoli, Michele, Gigantino, Vincenzo, De Cecio, Rossella, Rippa, Massimo, Petti, Lucia, Capone, Francesca, Vitagliano, Carlo, Milone, Maria R., Pucci, Biagio, Lombardi, Rita, Iannelli, Federica, Di Gennaro, Elena, Bruzzese, Francesca, Marchisio, Marco, Carriero, Maria V., Di Vizio, Dolores, Budillon, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639931/
https://www.ncbi.nlm.nih.gov/pubmed/31319863
http://dx.doi.org/10.1186/s13046-019-1317-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639931/
https://www.ncbi.nlm.nih.gov/pubmed/31319863
http://dx.doi.org/10.1186/s13046-019-1317-6

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