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Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation
BACKGROUND: Molecular markers for prostate cancer (PCa) are required to improve the early definition of patient outcomes. Atypically large extracellular vesicles (EVs), referred as “Large Oncosomes” (LO), have been identified in highly migratory and invasive PCa cells. We recently developed and char...
Autores principales: | Ciardiello, Chiara, Leone, Alessandra, Lanuti, Paola, Roca, Maria S., Moccia, Tania, Minciacchi, Valentina R., Minopoli, Michele, Gigantino, Vincenzo, De Cecio, Rossella, Rippa, Massimo, Petti, Lucia, Capone, Francesca, Vitagliano, Carlo, Milone, Maria R., Pucci, Biagio, Lombardi, Rita, Iannelli, Federica, Di Gennaro, Elena, Bruzzese, Francesca, Marchisio, Marco, Carriero, Maria V., Di Vizio, Dolores, Budillon, Alfredo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639931/ https://www.ncbi.nlm.nih.gov/pubmed/31319863 http://dx.doi.org/10.1186/s13046-019-1317-6 |
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