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Spatial UBE2N protein expression indicates genomic instability in colorectal cancers

BACKGROUND: One major hallmark of colorectal cancers (CRC) is genomic instability with its contribution to tumor heterogeneity and therapy resistance. To facilitate the investigation of intra-sample phenotypes and the de novo identification of tumor sub-populations, imaging mass spectrometry (IMS) p...

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Detalles Bibliográficos
Autores principales: Gemoll, Timo, Miroll, Elena, Klein, Oliver, Lischka, Annette, Eravci, Murat, Thorns, Christoph, Habermann, Jens K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639966/
https://www.ncbi.nlm.nih.gov/pubmed/31319803
http://dx.doi.org/10.1186/s12885-019-5856-1