Mechanosensing at the Nuclear Envelope by Nuclear Pore Complex Stretch Activation and Its Effect in Physiology and Pathology

Cell fate is correlated to mechanotransduction, in which forces transmitted by the cytoskeleton filaments alter the nuclear shape, affecting transcription factor import/export, cells transcription activity and chromatin distribution. There is in fact evidence that stem cells cultured in 3D environme...

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Detalles Bibliográficos
Autores principales: Donnaloja, F., Jacchetti, E., Soncini, M., Raimondi, M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640030/
https://www.ncbi.nlm.nih.gov/pubmed/31354529
http://dx.doi.org/10.3389/fphys.2019.00896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640030/
https://www.ncbi.nlm.nih.gov/pubmed/31354529
http://dx.doi.org/10.3389/fphys.2019.00896

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