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Discovery of All Three Types in Cartilaginous Fishes Enables Phylogenetic Resolution of the Origins and Evolution of Interferons

Interferons orchestrate host antiviral responses in jawed vertebrates. They are categorized into three classes; IFN1 and IFN3 are the primary antiviral cytokine lineages, while IFN2 responds to a broader variety of pathogens. The evolutionary relationships within and between these three classes have...

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Detalles Bibliográficos
Autores principales: Redmond, Anthony K., Zou, Jun, Secombes, Christopher J., Macqueen, Daniel J., Dooley, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640115/
https://www.ncbi.nlm.nih.gov/pubmed/31354716
http://dx.doi.org/10.3389/fimmu.2019.01558