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Can Targeting Non-Contiguous V-Regions With Paired-End Sequencing Improve 16S rRNA-Based Taxonomic Resolution of Microbiomes?: An In Silico Evaluation

Background: Next-generation sequencing (NGS) technologies have enabled probing of microbial diversity in different environmental niches with unprecedented sequencing depth. However, due to read-length limitations of popular NGS technologies, 16S amplicon sequencing-based microbiome studies rely on t...

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Detalles Bibliográficos
Autores principales: Pinna, Nishal Kumar, Dutta, Anirban, Monzoorul Haque, Mohammed, Mande, Sharmila S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640118/
https://www.ncbi.nlm.nih.gov/pubmed/31354793
http://dx.doi.org/10.3389/fgene.2019.00653