S-geranylgeranyl-L-glutathione is a ligand for human B-cell confinement receptor P2RY8

Germinal centers (GCs) are important sites for antibody diversification and affinity maturation and are also a common origin of B-cell malignancies. Although made up of motile cells, GCs are tightly confined within B-cell follicles. The cues promoting GC B-cell confinement are incompletely understoo...

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Detalles Bibliográficos
Autores principales: Lu, Erick, Wolfreys, Finn D., Muppidi, Jagan R., Xu, Ying, Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640153/
https://www.ncbi.nlm.nih.gov/pubmed/30842656
http://dx.doi.org/10.1038/s41586-019-1003-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640153/
https://www.ncbi.nlm.nih.gov/pubmed/30842656
http://dx.doi.org/10.1038/s41586-019-1003-z

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