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S-geranylgeranyl-L-glutathione is a ligand for human B-cell confinement receptor P2RY8
Germinal centers (GCs) are important sites for antibody diversification and affinity maturation and are also a common origin of B-cell malignancies. Although made up of motile cells, GCs are tightly confined within B-cell follicles. The cues promoting GC B-cell confinement are incompletely understoo...
Autores principales: | Lu, Erick, Wolfreys, Finn D., Muppidi, Jagan R., Xu, Ying, Cyster, Jason G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640153/ https://www.ncbi.nlm.nih.gov/pubmed/30842656 http://dx.doi.org/10.1038/s41586-019-1003-z |
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