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Practical, metal-free remote heteroarylation of amides via unactivated C(sp(3))–H bond functionalization

Development of practical methods for the production of multi-functionalized amides is one of the most important topics in both synthetic chemistry and drug discovery. Disclosed herein is a new, efficient, site-selective heteroarylation of amides via C(sp(3))–H bond functionalization. Amidyl radicals...

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Detalles Bibliográficos
Autores principales: Tang, Nana, Wu, Xinxin, Zhu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640195/
https://www.ncbi.nlm.nih.gov/pubmed/31391914
http://dx.doi.org/10.1039/c9sc02564b