OptMAVEn-2.0: De novo Design of Variable Antibody Regions against Targeted Antigen Epitopes

Monoclonal antibodies are becoming increasingly important therapeutic agents for the treatment of cancers, infectious diseases, and autoimmune disorders. However, laboratory-based methods of developing therapeutic monoclonal antibodies (e.g., immunized mice, hybridomas, and phage display) are time-c...

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Detalles Bibliográficos
Autores principales: Chowdhury, Ratul, Allan, Matthew F., Maranas, Costas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640672/
https://www.ncbi.nlm.nih.gov/pubmed/31544875
http://dx.doi.org/10.3390/antib7030023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640672/
https://www.ncbi.nlm.nih.gov/pubmed/31544875
http://dx.doi.org/10.3390/antib7030023

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