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Design Principles for Bispecific IgGs, Opportunities and Pitfalls of Artificial Disulfide Bonds

Bispecific antibodies (bsAbs) are antibodies with two binding sites directed at different antigens, enabling therapeutic strategies not achievable with conventional monoclonal antibodies (mAbs). Since bispecific antibodies are regarded as promising therapeutic agents, many different bispecific desig...

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Detalles Bibliográficos
Autores principales: Vaks, Lilach, Litvak-Greenfeld, Dana, Dror, Stav, Shefet-Carasso, LeeRon, Matatov, Galia, Nahary, Limor, Shapira, Shiran, Hakim, Rahely, Alroy, Iris, Benhar, Itai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640675/
https://www.ncbi.nlm.nih.gov/pubmed/31544879
http://dx.doi.org/10.3390/antib7030027