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Design Principles for Bispecific IgGs, Opportunities and Pitfalls of Artificial Disulfide Bonds
Bispecific antibodies (bsAbs) are antibodies with two binding sites directed at different antigens, enabling therapeutic strategies not achievable with conventional monoclonal antibodies (mAbs). Since bispecific antibodies are regarded as promising therapeutic agents, many different bispecific desig...
Autores principales: | Vaks, Lilach, Litvak-Greenfeld, Dana, Dror, Stav, Shefet-Carasso, LeeRon, Matatov, Galia, Nahary, Limor, Shapira, Shiran, Hakim, Rahely, Alroy, Iris, Benhar, Itai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640675/ https://www.ncbi.nlm.nih.gov/pubmed/31544879 http://dx.doi.org/10.3390/antib7030027 |
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