Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

Aβ is the toxic amyloid polypeptide responsible for Alzheimer’s disease (AD). Prevention and elimination of the Aβ misfolded aggregates are the promising therapeutic strategies for the AD treatments. Gammabody, the Aβ-Specific Single-domain (VH) antibody, recognizes Aβ aggregates with high affinity...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Mingzhen, Zheng, Jie, Nussinov, Ruth, Ma, Buyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640678/
https://www.ncbi.nlm.nih.gov/pubmed/31544877
http://dx.doi.org/10.3390/antib7030025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640678/
https://www.ncbi.nlm.nih.gov/pubmed/31544877
http://dx.doi.org/10.3390/antib7030025

Ejemplares similares