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Applicability of Traditional In Vitro Toxicity Tests for Assessing Adverse Effects of Monoclonal Antibodies: A Case Study of Rituximab and Trastuzumab

Monoclonal antibody (mAb) therapeutics have a promising outlook within the pharmaceutical industry having made positive strides in both research and development as well as commercialisation, however this development has been hampered by manufacturing failures and attrition. This study explores the a...

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Detalles Bibliográficos
Autores principales: Kizhedath, Arathi, Wilkinson, Simon, Glassey, Jarka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640679/
https://www.ncbi.nlm.nih.gov/pubmed/31544882
http://dx.doi.org/10.3390/antib7030030