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Thinking outside the Laboratory: Analyses of Antibody Structure and Dynamics within Different Solvent Environments in Molecular Dynamics (MD) Simulations

Monoclonal antibodies (mAbs) have revolutionized the biomedical field, directly influencing therapeutics and diagnostics in the biopharmaceutical industry, while continuing advances in computational efficiency have enabled molecular dynamics (MD) simulations to provide atomistic insight into the str...

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Detalles Bibliográficos
Autores principales: Al Qaraghuli, Mohammed M., Kubiak-Ossowska, Karina, Mulheran, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640683/
https://www.ncbi.nlm.nih.gov/pubmed/31544873
http://dx.doi.org/10.3390/antib7030021